RNF25 (ring finger protein 25)

2007-04-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
AO7
FUSION GENES

Other Information

Locus ID:

NCBI: 64320
MIM: 616014
HGNC: 14662
Ensembl: ENSG00000163481

Variants:

dbSNP: 64320
ClinVar: 64320
TCGA: ENSG00000163481
COSMIC: RNF25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163481ENST00000295704Q96BH1
ENSG00000163481ENST00000423170H7C219

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
105001821999RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.342
264758542015Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.9
127481882003RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit.8
297895422018RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-κB-mediated ERK reactivation.2

Citation

Dessen P

RNF25 (ring finger protein 25)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47140/rnf25