Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54538
MIM: 607528
HGNC: 17985
Ensembl: ENSG00000154133
Variants:
dbSNP: 54538
ClinVar: 54538
TCGA: ENSG00000154133
COSMIC: ROBO4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154133 | ENST00000306534 | Q8WZ75 |
| ENSG00000154133 | ENST00000533054 | B4DYV8 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38700874 | 2024 | The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration. | 0 |
| 38700874 | 2024 | The Role of SLIT3-ROBO4 Signaling in Endoplasmic Reticulum Stress-Induced Delayed Corneal Epithelial and Nerve Regeneration. | 0 |
| 37430272 | 2023 | The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy. | 2 |
| 37430272 | 2023 | The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy. | 2 |
| 35726111 | 2022 | Downregulation of ROBO4 in Pancreatic Cancer Serves as a Biomarker of Poor Prognosis and Indicates Increased Cell Motility and Proliferation Through Activation of MMP-9. | 4 |
| 35726111 | 2022 | Downregulation of ROBO4 in Pancreatic Cancer Serves as a Biomarker of Poor Prognosis and Indicates Increased Cell Motility and Proliferation Through Activation of MMP-9. | 4 |
| 33495827 | 2021 | miR-140-5p regulates vascular smooth muscle cell viability, migration and apoptosis by targeting ROBO4 gene expression in atherosclerosis. | 3 |
| 33495827 | 2021 | miR-140-5p regulates vascular smooth muscle cell viability, migration and apoptosis by targeting ROBO4 gene expression in atherosclerosis. | 3 |
| 30019121 | 2020 | Nuclear Localization of Robo is Associated with Better Survival in Bladder Cancer. | 1 |
| 32238717 | 2020 | PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells. | 2 |
| 32748548 | 2020 | Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease. | 12 |
| 33318575 | 2020 | Structural insights and evaluation of the potential impact of missense variants on the interactions of SLIT2 with ROBO1/4 in cancer progression. | 1 |
| 30019121 | 2020 | Nuclear Localization of Robo is Associated with Better Survival in Bladder Cancer. | 1 |
| 32238717 | 2020 | PRC2 Components Maintain DNA Hypermethylation of the Upstream Promoter and Regulate Robo4 Expression in Endothelial Cells. | 2 |
| 32748548 | 2020 | Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease. | 12 |
Citation
Dessen P
ROBO4 (roundabout guidance receptor 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45897/robo4
