Identity
HGNC
LOCATION
15q22.2
LOCUSID
ALIAS
IDDECA,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6095
MIM: 600825
HGNC: 10258
Ensembl: ENSG00000069667
Variants:
dbSNP: 6095
ClinVar: 6095
TCGA: ENSG00000069667
COSMIC: RORA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444987 | Multiple Sclerosis | Disease | ClinicalAnnotation | associated | PD | 31649263 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 19846067 | |
| PA449015 | citalopram | Chemical | ClinicalAnnotation | associated | PD | 19846067 | |
| PA450037 | interferon beta-1a | Chemical | ClinicalAnnotation | associated | PD | 31649263 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38177186 | 2024 | The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation. | 0 |
| 38177186 | 2024 | The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation. | 0 |
| 36834872 | 2023 | Novel Therapeutic Potential of Retinoid-Related Orphan Receptor α in Cardiovascular Diseases. | 1 |
| 36834872 | 2023 | Novel Therapeutic Potential of Retinoid-Related Orphan Receptor α in Cardiovascular Diseases. | 1 |
| 34995387 | 2022 | Disturbed expression of vitamin D and retinoic acid-related orphan receptors α and γ and of megalin in inflammatory skin diseases. | 4 |
| 35605663 | 2022 | Retinoid orphan nuclear receptor alpha (RORα) suppresses the epithelial-mesenchymal transition (EMT) by directly repressing Snail transcription. | 4 |
| 35636076 | 2022 | RORA polymorphisms are risk factors for allergic rhinitis susceptibility in the Shaanxi Han population. | 2 |
| 35878841 | 2022 | RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child. | 2 |
| 35934844 | 2022 | ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease. | 1 |
| 34995387 | 2022 | Disturbed expression of vitamin D and retinoic acid-related orphan receptors α and γ and of megalin in inflammatory skin diseases. | 4 |
| 35605663 | 2022 | Retinoid orphan nuclear receptor alpha (RORα) suppresses the epithelial-mesenchymal transition (EMT) by directly repressing Snail transcription. | 4 |
| 35636076 | 2022 | RORA polymorphisms are risk factors for allergic rhinitis susceptibility in the Shaanxi Han population. | 2 |
| 35878841 | 2022 | RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child. | 2 |
| 35934844 | 2022 | ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease. | 1 |
| 33091686 | 2021 | Aberrant functional connectivity between the suprachiasmatic nucleus and the superior temporal gyrus: Bridging RORA gene polymorphism with diurnal mood variation in major depressive disorder. | 5 |
Citation
Dessen P
RORA (RAR related orphan receptor A)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42142/rora
