RPE (ribulose-5-phosphate-3-epimerase)

2014-11-01  

Identity

HGNC
RPE
LOCATION
2q34
LOCUSID
6120
ALIAS
RPE2-1

Other Information

Locus ID:

NCBI: 6120
MIM: 180480
HGNC: 10293
Ensembl: ENSG00000197713

Variants:

dbSNP: 6120
ClinVar: 6120
TCGA: ENSG00000197713
COSMIC: RPE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197713ENST00000354506Q96AT9
ENSG00000197713ENST00000359429Q96AT9
ENSG00000197713ENST00000408981C9J6A7
ENSG00000197713ENST00000411934Q96AT9
ENSG00000197713ENST00000429907C9IYE8
ENSG00000197713ENST00000429921Q96AT9
ENSG00000197713ENST00000435437C9J9T0
ENSG00000197713ENST00000436630Q96AT9
ENSG00000197713ENST00000438191F8WBT4
ENSG00000197713ENST00000438204Q96AT9
ENSG00000197713ENST00000438265E7ESZ6
ENSG00000197713ENST00000441588C9JCL8
ENSG00000197713ENST00000445268C9J8S0
ENSG00000197713ENST00000452025C9IZU8
ENSG00000197713ENST00000453724E9PBG9
ENSG00000197713ENST00000454822Q96AT9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Pentose phosphate pathwayKEGGko00030
Pentose and glucuronate interconversionsKEGGko00040
Pentose phosphate pathwayKEGGhsa00030
Pentose and glucuronate interconversionsKEGGhsa00040
Metabolic pathwaysKEGGhsa01100
Pentose phosphate pathway (Pentose phosphate cycle)KEGGhsa_M00004
Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5PKEGGhsa_M00007
Pentose phosphate pathway (Pentose phosphate cycle)KEGGM00004
Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5PKEGGM00007
Biosynthesis of amino acidsKEGGhsa01230
Biosynthesis of amino acidsKEGGko01230
Carbon metabolismKEGGhsa01200
Carbon metabolismKEGGko01200
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Pentose phosphate pathway (hexose monophosphate shunt)REACTOMER-HSA-71336

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
209239652011Conversion of D-ribulose 5-phosphate to D-xylulose 5-phosphate: new insights from structural and biochemical studies on human RPE.7

Citation

Dessen P

RPE (ribulose-5-phosphate-3-epimerase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72777/rpe