Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RPL12 (ribosomal protein L12)

Identity

Alias_symbol (synonym)L12
Other alias
HGNC (Hugo) RPL12
LocusID (NCBI) 6136
Atlas_Id 72787
Location 9q33.3  [Link to chromosome band 9q33]
Location_base_pair Starts at 127447674 and ends at 127451432 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IKZF3 (17q12) / RPL12 (9q33.3)RPL12 (9q33.3) / RGCC (13q14.11)RPL12 (9q33.3) / RPL12 (9q33.3)
SON (21q22.11) / RPL12 (9q33.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RPL12   10302
Cards
Entrez_Gene (NCBI)RPL12  6136  ribosomal protein L12
AliasesL12
GeneCards (Weizmann)RPL12
Ensembl hg19 (Hinxton)ENSG00000197958 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197958 [Gene_View]  ENSG00000197958 [Sequence]  chr9:127447674-127451432 [Contig_View]  RPL12 [Vega]
ICGC DataPortalENSG00000197958
TCGA cBioPortalRPL12
AceView (NCBI)RPL12
Genatlas (Paris)RPL12
WikiGenes6136
SOURCE (Princeton)RPL12
Genetics Home Reference (NIH)RPL12
Genomic and cartography
GoldenPath hg38 (UCSC)RPL12  -     chr9:127447674-127451432 -  9q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPL12  -     9q33.3   [Description]    (hg19-Feb_2009)
GoldenPathRPL12 - 9q33.3 [CytoView hg19]  RPL12 - 9q33.3 [CytoView hg38]
ImmunoBaseENSG00000197958
Mapping of homologs : NCBIRPL12 [Mapview hg19]  RPL12 [Mapview hg38]
OMIM180475   
Gene and transcription
Genbank (Entrez)AF037643 AK026526 AK057602 BC050644 BC059950
RefSeq transcript (Entrez)NM_000976
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPL12
Cluster EST : UnigeneHs.408054 [ NCBI ]
CGAP (NCI)Hs.408054
Alternative Splicing GalleryENSG00000197958
Gene ExpressionRPL12 [ NCBI-GEO ]   RPL12 [ EBI - ARRAY_EXPRESS ]   RPL12 [ SEEK ]   RPL12 [ MEM ]
Gene Expression Viewer (FireBrowse)RPL12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6136
GTEX Portal (Tissue expression)RPL12
Human Protein AtlasENSG00000197958-RPL12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30050   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30050  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30050
Splice isoforms : SwissVarP30050
PhosPhoSitePlusP30050
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_L11 (PS00359)   
Domains : Interpro (EBI)Ribosomal_L11/L12    Ribosomal_L11/L12_N_sf    Ribosomal_L11_C    Ribosomal_L11_C_sf    Ribosomal_L11_CS    Ribosomal_L11_N   
Domain families : Pfam (Sanger)Ribosomal_L11 (PF00298)    Ribosomal_L11_N (PF03946)   
Domain families : Pfam (NCBI)pfam00298    pfam03946   
Domain families : Smart (EMBL)RL11 (SM00649)  
Conserved Domain (NCBI)RPL12
DMDM Disease mutations6136
Blocks (Seattle)RPL12
PDB (RSDB)4V6X    5A8L    5AJ0   
PDB Europe4V6X    5A8L    5AJ0   
PDB (PDBSum)4V6X    5A8L    5AJ0   
PDB (IMB)4V6X    5A8L    5AJ0   
Structural Biology KnowledgeBase4V6X    5A8L    5AJ0   
SCOP (Structural Classification of Proteins)4V6X    5A8L    5AJ0   
CATH (Classification of proteins structures)4V6X    5A8L    5AJ0   
SuperfamilyP30050
Human Protein Atlas [tissue]ENSG00000197958-RPL12 [tissue]
Peptide AtlasP30050
HPRD01603
IPIIPI00024933   IPI00816063   
Protein Interaction databases
DIP (DOE-UCLA)P30050
IntAct (EBI)P30050
FunCoupENSG00000197958
BioGRIDRPL12
STRING (EMBL)RPL12
ZODIACRPL12
Ontologies - Pathways
QuickGOP30050
Ontology : AmiGOribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleolus  cytosol  focal adhesion  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  postsynaptic density  large ribosomal subunit  membrane  viral transcription  rRNA binding  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  extracellular exosome  large ribosomal subunit rRNA binding  
Ontology : EGO-EBIribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleolus  cytosol  focal adhesion  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  postsynaptic density  large ribosomal subunit  membrane  viral transcription  rRNA binding  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  extracellular exosome  large ribosomal subunit rRNA binding  
Pathways : KEGGRibosome   
NDEx NetworkRPL12
Atlas of Cancer Signalling NetworkRPL12
Wikipedia pathwaysRPL12
Orthology - Evolution
OrthoDB6136
GeneTree (enSembl)ENSG00000197958
Phylogenetic Trees/Animal Genes : TreeFamRPL12
HOGENOMP30050
Homologs : HomoloGeneRPL12
Homology/Alignments : Family Browser (UCSC)RPL12
Gene fusions - Rearrangements
Fusion : QuiverRPL12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPL12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPL12
dbVarRPL12
ClinVarRPL12
1000_GenomesRPL12 
Exome Variant ServerRPL12
ExAC (Exome Aggregation Consortium)ENSG00000197958
GNOMAD BrowserENSG00000197958
Varsome BrowserRPL12
Genetic variants : HAPMAP6136
Genomic Variants (DGV)RPL12 [DGVbeta]
DECIPHERRPL12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPL12 
Mutations
ICGC Data PortalRPL12 
TCGA Data PortalRPL12 
Broad Tumor PortalRPL12
OASIS PortalRPL12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPL12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRPL12
Mutations and Diseases : HGMDRPL12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPL12
DgiDB (Drug Gene Interaction Database)RPL12
DoCM (Curated mutations)RPL12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPL12 (select a term)
intoGenRPL12
Cancer3DRPL12(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180475   
Orphanet
DisGeNETRPL12
MedgenRPL12
Genetic Testing Registry RPL12
NextProtP30050 [Medical]
TSGene6136
GENETestsRPL12
Target ValidationRPL12
Huge Navigator RPL12 [HugePedia]
snp3D : Map Gene to Disease6136
BioCentury BCIQRPL12
ClinGenRPL12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6136
Chemical/Pharm GKB GenePA34665
Clinical trialRPL12
Miscellaneous
canSAR (ICR)RPL12 (select the gene name)
DataMed IndexRPL12
Probes
Litterature
PubMed108 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPL12
EVEXRPL12
GoPubMedRPL12
iHOPRPL12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:03:53 CEST 2019
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