Atlas of Genetics and Cytogenetics in Oncology and Haematology

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RPLP0 (ribosomal protein lateral stalk subunit P0)

Identity

Alias_namesribosomal protein, large, P0
Alias_symbol (synonym)PRLP0
P0
L10E
RPP0
LP0
Other alias
HGNC (Hugo) RPLP0
LocusID (NCBI) 6175
Atlas_Id 50046
Location 12q24.23  [Link to chromosome band 12q24]
Location_base_pair Starts at 120196700 and ends at 120201211 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CNPY2 (12q13.3) / RPLP0 (12q24.23)PPP3CB (10q22.2) / RPLP0 (12q24.23)RHOD (11q13.2) / RPLP0 (12q24.23)
RPLP0 (12q24.23) / CDK5 (7q36.1)RPLP0 (12q24.23) / CDS1 (4q21.23)RPLP0 (12q24.23) / MTMR10 (15q13.3)
RPLP0 (12q24.23) / NDUFA13 (19p13.11)RPLP0P2 (11q12.2) / RPLP0 (12q24.23)RTEL1 (20q13.33) / RPLP0 (12q24.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RPLP0   10371
Cards
Entrez_Gene (NCBI)RPLP0  6175  ribosomal protein lateral stalk subunit P0
AliasesL10E; LP0; P0; PRLP0; 
RPP0
GeneCards (Weizmann)RPLP0
Ensembl hg19 (Hinxton)ENSG00000089157 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089157 [Gene_View]  ENSG00000089157 [Sequence]  chr12:120196700-120201211 [Contig_View]  RPLP0 [Vega]
ICGC DataPortalENSG00000089157
TCGA cBioPortalRPLP0
AceView (NCBI)RPLP0
Genatlas (Paris)RPLP0
WikiGenes6175
SOURCE (Princeton)RPLP0
Genetics Home Reference (NIH)RPLP0
Genomic and cartography
GoldenPath hg38 (UCSC)RPLP0  -     chr12:120196700-120201211 -  12q24.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPLP0  -     12q24.23   [Description]    (hg19-Feb_2009)
GoldenPathRPLP0 - 12q24.23 [CytoView hg19]  RPLP0 - 12q24.23 [CytoView hg38]
ImmunoBaseENSG00000089157
Mapping of homologs : NCBIRPLP0 [Mapview hg19]  RPLP0 [Mapview hg38]
OMIM180510   
Gene and transcription
Genbank (Entrez)AF274958 AK001313 AK129754 AK129823 AK222468
RefSeq transcript (Entrez)NM_001002 NM_053275
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPLP0
Cluster EST : UnigeneHs.546285 [ NCBI ]
CGAP (NCI)Hs.546285
Alternative Splicing GalleryENSG00000089157
Gene ExpressionRPLP0 [ NCBI-GEO ]   RPLP0 [ EBI - ARRAY_EXPRESS ]   RPLP0 [ SEEK ]   RPLP0 [ MEM ]
Gene Expression Viewer (FireBrowse)RPLP0 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6175
GTEX Portal (Tissue expression)RPLP0
Human Protein AtlasENSG00000089157-RPLP0 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05388   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05388  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05388
Splice isoforms : SwissVarP05388
PhosPhoSitePlusP05388
Domains : Interpro (EBI)L10E_eukaryotes    Ribosomal_L10P   
Domain families : Pfam (Sanger)Ribosomal_L10 (PF00466)   
Domain families : Pfam (NCBI)pfam00466   
Conserved Domain (NCBI)RPLP0
DMDM Disease mutations6175
Blocks (Seattle)RPLP0
PDB (RSDB)4V6W    4V6X    5AJ0   
PDB Europe4V6W    4V6X    5AJ0   
PDB (PDBSum)4V6W    4V6X    5AJ0   
PDB (IMB)4V6W    4V6X    5AJ0   
Structural Biology KnowledgeBase4V6W    4V6X    5AJ0   
SCOP (Structural Classification of Proteins)4V6W    4V6X    5AJ0   
CATH (Classification of proteins structures)4V6W    4V6X    5AJ0   
SuperfamilyP05388
Human Protein Atlas [tissue]ENSG00000089157-RPLP0 [tissue]
Peptide AtlasP05388
HPRD01610
IPIIPI00008530   IPI00556485   IPI00382461   IPI01021777   IPI01022462   IPI01022636   IPI01020986   IPI01021139   IPI01022333   IPI01022174   IPI01023074   IPI01021320   IPI01021490   IPI01022043   IPI01021889   
Protein Interaction databases
DIP (DOE-UCLA)P05388
IntAct (EBI)P05388
FunCoupENSG00000089157
BioGRIDRPLP0
STRING (EMBL)RPLP0
ZODIACRPLP0
Ontologies - Pathways
QuickGOP05388
Ontology : AmiGOribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  focal adhesion  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  postsynaptic density  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  interleukin-12-mediated signaling pathway  cytoplasmic ribonucleoprotein granule  extracellular exosome  large ribosomal subunit rRNA binding  postsynapse  postsynapse  ribonucleoprotein complex  
Ontology : EGO-EBIribosomal large subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  cytoplasmic translation  RNA binding  structural constituent of ribosome  structural constituent of ribosome  structural constituent of ribosome  protein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  focal adhesion  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  postsynaptic density  postsynaptic density  membrane  viral transcription  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  cytosolic large ribosomal subunit  interleukin-12-mediated signaling pathway  cytoplasmic ribonucleoprotein granule  extracellular exosome  large ribosomal subunit rRNA binding  postsynapse  postsynapse  ribonucleoprotein complex  
Pathways : KEGGRibosome   
NDEx NetworkRPLP0
Atlas of Cancer Signalling NetworkRPLP0
Wikipedia pathwaysRPLP0
Orthology - Evolution
OrthoDB6175
GeneTree (enSembl)ENSG00000089157
Phylogenetic Trees/Animal Genes : TreeFamRPLP0
HOGENOMP05388
Homologs : HomoloGeneRPLP0
Homology/Alignments : Family Browser (UCSC)RPLP0
Gene fusions - Rearrangements
Fusion Cancer (Beijing)RPLP0P2 [11q12.2]  -  RPLP0 [12q24.23]  [FUSC001094]
Fusion : QuiverRPLP0
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPLP0 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPLP0
dbVarRPLP0
ClinVarRPLP0
1000_GenomesRPLP0 
Exome Variant ServerRPLP0
ExAC (Exome Aggregation Consortium)ENSG00000089157
GNOMAD BrowserENSG00000089157
Varsome BrowserRPLP0
Genetic variants : HAPMAP6175
Genomic Variants (DGV)RPLP0 [DGVbeta]
DECIPHERRPLP0 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPLP0 
Mutations
ICGC Data PortalRPLP0 
TCGA Data PortalRPLP0 
Broad Tumor PortalRPLP0
OASIS PortalRPLP0 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPLP0  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRPLP0
Mutations and Diseases : HGMDRPLP0
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPLP0
DgiDB (Drug Gene Interaction Database)RPLP0
DoCM (Curated mutations)RPLP0 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPLP0 (select a term)
intoGenRPLP0
Cancer3DRPLP0(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180510   
Orphanet
DisGeNETRPLP0
MedgenRPLP0
Genetic Testing Registry RPLP0
NextProtP05388 [Medical]
TSGene6175
GENETestsRPLP0
Target ValidationRPLP0
Huge Navigator RPLP0 [HugePedia]
snp3D : Map Gene to Disease6175
BioCentury BCIQRPLP0
ClinGenRPLP0
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6175
Chemical/Pharm GKB GenePA34772
Clinical trialRPLP0
Miscellaneous
canSAR (ICR)RPLP0 (select the gene name)
DataMed IndexRPLP0
Probes
Litterature
PubMed161 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPLP0
EVEXRPLP0
GoPubMedRPLP0
iHOPRPLP0
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:05:36 CET 2019
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