RTN4R (reticulon 4 receptor)

2010-07-01  

Identity

HGNC
RTN4R
LOCATION
22q11.21
LOCUSID
65078
ALIAS
NGR,NOGOR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65078
MIM: 605566
HGNC: 18601
Ensembl: ENSG00000040608

Variants:

dbSNP: 65078
ClinVar: 65078
TCGA: ENSG00000040608
COSMIC: RTN4R

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000040608ENST00000043402Q9BZR6
ENSG00000040608ENST00000416372H7C0V4
ENSG00000040608ENST00000425986H7C215

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
120683102002Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth.243
124222172002P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp.218
208441382010Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity.61
190522072008Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.42
190522072008Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.42
171827782006Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice.41
155320242004Mutations of the Nogo-66 receptor (RTN4R) gene in schizophrenia.34
155320242004Mutations of the Nogo-66 receptor (RTN4R) gene in schizophrenia.34
123785892002Nogo-receptor gene activity: cellular localization and developmental regulation of mRNA in mice and humans.33
203989082010Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.32

Citation

Dessen P

RTN4R (reticulon 4 receptor)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51564/rtn4r