RTN4RL1 (reticulon 4 receptor like 1)

2021-06-01  

Identity

HGNC
LOCATION
17p13.3
LOCUSID
ALIAS
NGRH2,NgR3

Other Information

Locus ID:

NCBI: 146760
MIM: 610461
HGNC: 21329
Ensembl: ENSG00000185924

Variants:

dbSNP: 146760
ClinVar: 146760
TCGA: ENSG00000185924
COSMIC: RTN4RL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185924ENST00000331238Q86UN2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
146648092003Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems.30
221336822011Nogo receptor 3, a paralog of Nogo-66 receptor 1 (NgR1), may function as a NgR1 co-receptor for Nogo-66.5
293270672018Overexpression of Nogo receptor 3 (NgR3) correlates with poor prognosis and contributes to the migration of epithelial cells of nasopharyngeal carcinoma patients.3
263839232015Duplication of 10q22.3-q23.3 encompassing BMPR1A and NGR3 associated with congenital heart disease, microcephaly, and mild intellectual disability.2

Citation

Dessen P

RTN4RL1 (reticulon 4 receptor like 1)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58171/rtn4rl1