RTN4RL2 (reticulon 4 receptor like 2)

2014-11-01  

Identity

HGNC
RTN4RL2
LOCATION
11q12.1
LOCUSID
349667
ALIAS
NGRH1,NgR2

Other Information

Locus ID:

NCBI: 349667
MIM: 610462
HGNC: 23053
Ensembl: ENSG00000186907

Variants:

dbSNP: 349667
ClinVar: 349667
TCGA: ENSG00000186907
COSMIC: RTN4RL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186907ENST00000335099Q86UN3
ENSG00000186907ENST00000395120Q86UN3
ENSG00000186907ENST00000533205G3V1D7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

References

Pubmed IDYearTitleCitations
146648092003Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems.30
219062732011Nogo receptor is involved in the adhesion of dendritic cells to myelin.8
249561332014Structural features of the Nogo receptor signaling complexes at the neuron/myelin interface.8
156294372005Ectodomain shedding of human Nogo-66 receptor homologue-1 by zinc metalloproteinases.0
183374052008Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.0

Citation

Dessen P

RTN4RL2 (reticulon 4 receptor like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72927/rtn4rl2