RXRG (retinoid X receptor gamma)

2003-05-01  

Identity

HGNC
RXRG
LOCATION
1q23.3
LOCUSID
6258
ALIAS
NR2B3,RXRC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6258
MIM: 180247
HGNC: 10479
Ensembl: ENSG00000143171

Variants:

dbSNP: 6258
ClinVar: 6258
TCGA: ENSG00000143171
COSMIC: RXRG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143171ENST00000359842P48443
ENSG00000143171ENST00000359842F1D8Q7
ENSG00000143171ENST00000619224A0A087WZ88

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
PPAR signaling pathwayKEGGko03320
Adipocytokine signaling pathwayKEGGko04920
Thyroid cancerKEGGko05216
Small cell lung cancerKEGGko05222
Non-small cell lung cancerKEGGko05223
PPAR signaling pathwayKEGGhsa03320
Adipocytokine signaling pathwayKEGGhsa04920
Pathways in cancerKEGGhsa05200
Thyroid cancerKEGGhsa05216
Small cell lung cancerKEGGhsa05222
Non-small cell lung cancerKEGGhsa05223
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Thyroid hormone signaling pathwayKEGGhsa04919
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Nuclear Receptor transcription pathwayREACTOMER-HSA-383280
Th17 cell differentiationKEGGko04659
Th17 cell differentiationKEGGhsa04659

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
211319502011Retinoid X receptor gamma signaling accelerates CNS remyelination.146
156086922004Retinoid X receptors: X-ploring their (patho)physiological functions.89
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
197543112009Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).53
195361752009Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.30
208555652010Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.27
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.26
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.20
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
183980472008Single nucleotide polymorphisms in obesity-related genes and the risk of esophageal cancers.17

Citation

Dessen P

RXRG (retinoid X receptor gamma)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42188/rxrg