S100A14 (S100 calcium binding protein A14)

2009-06-01  

Identity

HGNC
S100A14
LOCATION
1q21.3
LOCUSID
57402
ALIAS
BCMP84,S100A15
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57402
MIM: 607986
HGNC: 18901
Ensembl: ENSG00000189334

Variants:

dbSNP: 57402
ClinVar: 57402
TCGA: ENSG00000189334
COSMIC: S100A14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189334ENST00000344616Q9HCY8
ENSG00000189334ENST00000368701Q9HCY8
ENSG00000189334ENST00000368702Q9HCY8
ENSG00000189334ENST00000476873Q9HCY8

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
215594032011S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).33
224516552012Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulation.31
199568632010Expression status of S100A14 and S100A4 correlates with metastatic potential and clinical outcome in colorectal cancer after surgery.25
258844182015Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion.21
238861912013S100A14 promotes the growth and metastasis of hepatocellular carcinoma.18
220328982012S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.17
242855422014S100A14, a member of the EF-hand calcium-binding proteins, is overexpressed in breast cancer and acts as a modulator of HER2 signaling.17
193518282009Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma.16
241072962013S100A14: novel modulator of terminal differentiation in esophageal cancer.12
249398562014The role of S100A14 in epithelial ovarian tumors.12

Citation

Dessen P

S100A14 (S100 calcium binding protein A14)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50987/s100a14