S100A16 (S100 calcium binding protein A16)

2015-08-01  

Identity

HGNC
S100A16
LOCATION
1q21.3
LOCUSID
140576
ALIAS
AAG13,DT1P1A7,S100F
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 140576
MIM: 617437
HGNC: 20441
Ensembl: ENSG00000188643

Variants:

dbSNP: 140576
ClinVar: 140576
TCGA: ENSG00000188643
COSMIC: S100A16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188643ENST00000368703Q96FQ6
ENSG00000188643ENST00000368704Q96FQ6
ENSG00000188643ENST00000368705Q96FQ6
ENSG00000188643ENST00000368706Q96FQ6

Expression (GTEx)

0
500
1000
1500
2000
2500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
258844182015Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion.21
252873622014Up-regulation of S100A16 expression promotes epithelial-mesenchymal transition via Notch1 pathway in breast cancer.16
272405912016S100A16 promotes cell proliferation and metastasis via AKT and ERK cell signaling pathways in human prostate cancer.14
263537542015S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma.10
288764682018S100A16 is a prognostic marker for colorectal cancer.8
210461862011Structural characterization of human S100A16, a low-affinity calcium binder.5
301833742019Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.3
293207532018Prognostic significance of S100A16 subcellular localization in lung adenocarcinoma.1
309163752019S100A16 suppresses the growth and survival of leukaemia cells and correlates with relapse and relapse free survival in adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia.0
310084872019[S100 calcium binding protein A16 promotes fat synthesis through endoplasmic reticulum stress in HepG2 cells].0

Citation

Dessen P

S100A16 (S100 calcium binding protein A16)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55330/s100a16