SALL2 (spalt like transcription factor 2)

2007-02-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
COLB,HSAL2,Sal-2,ZNF795,p150(Sal2)
FUSION GENES

Other Information

Locus ID:

NCBI: 6297
MIM: 602219
HGNC: 10526
Ensembl: ENSG00000165821

Variants:

dbSNP: 6297
ClinVar: 6297
TCGA: ENSG00000165821
COSMIC: SALL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165821ENST00000450879E7EW59
ENSG00000165821ENST00000537235F5H433
ENSG00000165821ENST00000541965F5H1G6
ENSG00000165821ENST00000546363H0YFS7
ENSG00000165821ENST00000611430A0A087X1T9
ENSG00000165821ENST00000613414A0A0B4J2F7
ENSG00000165821ENST00000614342Q9Y467

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192479462009Regulation and function of Spalt proteins during animal development.52
150827822004p150(Sal2) is a p53-independent regulator of p21(WAF1/CIP).29
145076522003Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.27
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
191319672009Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth.15
232735472013Promoter methylation of the SALL2 tumor suppressor gene in ovarian cancers.14
244129332014Mutation of SALL2 causes recessive ocular coloboma in humans and mice.12
213625082011DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150(Sal2).11
212282192011Transcriptional and post-translational regulation of the quiescence factor and putative tumor suppressor p150(Sal2).8
230295312012The polyoma virus large T binding protein p150 is a transcriptional repressor of c-MYC.8

Citation

Dessen P

SALL2 (spalt like transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46308/sall2