SAMD4B (sterile alpha motif domain containing 4B)

2014-08-01  

Identity

HGNC
SAMD4B
LOCATION
19q13.2
LOCUSID
55095
ALIAS
SMGB,Smaug2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55095
HGNC: 25492
Ensembl: ENSG00000179134

Variants:

dbSNP: 55095
ClinVar: 55095
TCGA: ENSG00000179134
COSMIC: SAMD4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179134ENST00000314471Q5PRF9
ENSG00000179134ENST00000314471A0A024R0N7
ENSG00000179134ENST00000596368M0R0X3
ENSG00000179134ENST00000598605M0QX45
ENSG00000179134ENST00000598913M0QZ22
ENSG00000179134ENST00000599712M0QY61
ENSG00000179134ENST00000600018M0QZW7
ENSG00000179134ENST00000602243M0QXV2
ENSG00000179134ENST00000610417Q5PRF9
ENSG00000179134ENST00000610417A0A024R0N7
ENSG00000179134ENST00000611159A0A087WZT0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
205100202010SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity.3

Citation

Dessen P

SAMD4B (sterile alpha motif domain containing 4B)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54598/samd4b