SAP30 (Sin3A associated protein 30)

2003-05-01  

Identity

HGNC
LOCATION
4q34.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 8819
MIM: 603378
HGNC: 10532
Ensembl: ENSG00000164105

Variants:

dbSNP: 8819
ClinVar: 8819
TCGA: ENSG00000164105
COSMIC: SAP30

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164105ENST00000296504O75446

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HDACs deacetylate histonesREACTOMER-HSA-3214815

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376556632023SAP30 promotes breast tumor progression by bridging the transcriptional corepressor SIN3 complex and MLL1.0
381541012023Reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of SAP30 on cell apoptosis, ROS and MDA production in cerebral ischemic stroke.0
376556632023SAP30 promotes breast tumor progression by bridging the transcriptional corepressor SIN3 complex and MLL1.0
381541012023Reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of SAP30 on cell apoptosis, ROS and MDA production in cerebral ischemic stroke.0
363028552022Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.8
363028552022Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia.8
299895762018[Transcription Factor SAP30 Is Involved in the Activation of NETO2 Gene Expression in Clear Cell Renal Cell Carcinoma].8
299895762018[Transcription Factor SAP30 Is Involved in the Activation of NETO2 Gene Expression in Clear Cell Renal Cell Carcinoma].8
204783932010SLy2 targets the nuclear SAP30/HDAC1 complex.10
204783932010SLy2 targets the nuclear SAP30/HDAC1 complex.10
190152402009DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides.33
190152402009DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides.33
176729182007Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.20
178976152007Papillomavirus binding factor binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex.12
176729182007Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.20

Citation

Dessen P

SAP30 (Sin3A associated protein 30)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42202/sap30