SATB2 (SATB homeobox 2)

2007-02-01  

Identity

HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
GLSS
FUSION GENES

Other Information

Locus ID:

NCBI: 23314
MIM: 608148
HGNC: 21637
Ensembl: ENSG00000119042

Variants:

dbSNP: 23314
ClinVar: 23314
TCGA: ENSG00000119042
COSMIC: SATB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119042ENST00000260926Q9UPW6
ENSG00000119042ENST00000260926A0A024R3U6
ENSG00000119042ENST00000417098Q9UPW6
ENSG00000119042ENST00000417098A0A024R3U6
ENSG00000119042ENST00000428695Q9UPW6
ENSG00000119042ENST00000440919F8WCV6
ENSG00000119042ENST00000443023C9JR56
ENSG00000119042ENST00000457245Q9UPW6
ENSG00000119042ENST00000457245A0A024R3U6
ENSG00000119042ENST00000614512Q9UPW6

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
129154432003Identification of SATB2 as the cleft palate gene on 2q32-q33.81
163278842005Medical sequencing of candidate genes for nonsyndromic cleft lip and palate.70
216775342011SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.46
196683352009Small deletions of SATB2 cause some of the clinical features of the 2q33.1 microdeletion syndrome.43
243864672013Elevated microRNA-31 expression regulates colorectal cancer progression by repressing its target gene SATB2.41
245658402014Effects of miR-31 on the osteogenesis of human mesenchymal stem cells.32
248847322014microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis.32
237014292013SATB2 is a novel marker of osteoblastic differentiation in bone and soft tissue tumours.24
208298812010SATB2 augments ΔNp63α in head and neck squamous cell carcinoma.22
253235502014Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma.21

Citation

Dessen P

SATB2 (SATB homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46117/satb2