SCARA5 (scavenger receptor class A member 5)

2017-01-01  

Identity

HGNC
LOCATION
8p21.1
LOCUSID
ALIAS
NET33,Tesr
FUSION GENES

Other Information

Locus ID:

NCBI: 286133
MIM: 611306
HGNC: 28701
Ensembl: ENSG00000168079

Variants:

dbSNP: 286133
ClinVar: 286133
TCGA: ENSG00000168079
COSMIC: SCARA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168079ENST00000354914Q6ZMJ2
ENSG00000168079ENST00000380385Q6ZMJ2
ENSG00000168079ENST00000518030Q6ZMJ2
ENSG00000168079ENST00000524352Q6ZMJ2

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Binding and Uptake of Ligands by Scavenger ReceptorsREACTOMER-HSA-2173782
Scavenging by Class A ReceptorsREACTOMER-HSA-3000480

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
221380342012Scavenger receptor-mediated uptake of cell-penetrating peptide nanocomplexes with oligonucleotides.29
218581782011Ectopic pregnancy as a model to identify endometrial genes and signaling pathways important in decidualization and regulated by local trophoblast.13
210293582011Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.5
290199002017Methylation analysis of p16, SLIT2, SCARA5, and Runx3 genes in hepatocellular carcinoma.4
302492892018SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation.4
270355662016Knockdown of SCARA5 inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppression of the PDGF signaling pathway.3
277936642016Rock2 promotes RCC proliferation by decreasing SCARA5 expression through β-catenin/TCF4 signaling.3
291899912018CSN5 Promotes Hepatocellular Carcinoma Progression by SCARA5 Inhibition Through Suppressing β-Catenin Ubiquitination.3
252596502014L-ferritin binding to scara5: a new iron traffic pathway potentially implicated in retinopathy.0

Citation

Dessen P

SCARA5 (scavenger receptor class A member 5)

Atlas Genet Cytogenet Oncol Haematol. 2017-01-01

Online version: http://atlasgeneticsoncology.org/gene/56703/scara5