Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10389
MIM: 300208
HGNC: 10581
Ensembl: ENSG00000102098
Variants:
dbSNP: 10389
ClinVar: 10389
TCGA: ENSG00000102098
COSMIC: SCML2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102098 | ENST00000251900 | Q9UQR0 |
| ENSG00000102098 | ENST00000398048 | Q9UQR0 |
| ENSG00000102098 | ENST00000420857 | H0Y6S1 |
| ENSG00000102098 | ENST00000665583 | B4DRC2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34816637 | 2021 | Sex Comb on Midleg Like-2 Accelerates Hepatocellular Carcinoma Cell Proliferation and Metastasis by Activating Wnt/β-Catenin/EMT Signaling. | 1 |
| 34816637 | 2021 | Sex Comb on Midleg Like-2 Accelerates Hepatocellular Carcinoma Cell Proliferation and Metastasis by Activating Wnt/β-Catenin/EMT Signaling. | 1 |
| 25605328 | 2015 | USP7 cooperates with SCML2 to regulate the activity of PRC1. | 29 |
| 25605328 | 2015 | USP7 cooperates with SCML2 to regulate the activity of PRC1. | 29 |
| 24727478 | 2014 | Solution NMR structure of the DNA-binding domain from Scml2 (sex comb on midleg-like 2). | 6 |
| 24986859 | 2014 | Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes. | 33 |
| 24727478 | 2014 | Solution NMR structure of the DNA-binding domain from Scml2 (sex comb on midleg-like 2). | 6 |
| 24986859 | 2014 | Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes. | 33 |
| 18706910 | 2008 | The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. | 24 |
| 18706910 | 2008 | The malignant brain tumor repeats of human SCML2 bind to peptides containing monomethylated lysine. | 24 |
| 12952983 | 2003 | Crystal structure of the malignant brain tumor (MBT) repeats in Sex Comb on Midleg-like 2 (SCML2). | 25 |
| 12952983 | 2003 | Crystal structure of the malignant brain tumor (MBT) repeats in Sex Comb on Midleg-like 2 (SCML2). | 25 |
Citation
Dessen P
SCML2 (Scm polycomb group protein like 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47100/scml2
