Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6341
MIM: 603644
HGNC: 10603
Ensembl: ENSG00000133028
Variants:
dbSNP: 6341
ClinVar: 6341
TCGA: ENSG00000133028
COSMIC: SCO1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000133028 | ENST00000255390 | O75880 |
| ENSG00000133028 | ENST00000577335 | J3QR42 |
| ENSG00000133028 | ENST00000577427 | J3QL56 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26160915 | 2015 | COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2. | 53 |
| 26351686 | 2015 | Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of CuA in human cytochrome oxidase. | 35 |
| 26160915 | 2015 | COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2. | 53 |
| 26351686 | 2015 | Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of CuA in human cytochrome oxidase. | 35 |
| 24403053 | 2014 | Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase. | 52 |
| 24403053 | 2014 | Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase. | 52 |
| 23345593 | 2013 | COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. | 0 |
| 23345593 | 2013 | COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. | 0 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20864674 | 2010 | Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease. | 5 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20864674 | 2010 | Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease. | 5 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19295170 | 2009 | Loss of function of Sco1 and its interaction with cytochrome c oxidase. | 46 |
Citation
Dessen P
SCO1 (synthesis of cytochrome C oxidase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47018/sco1
