Identity
HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
CEGB1,CEGF1,CEGP1,scube/You
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57758
MIM: 611747
HGNC: 30425
Ensembl: ENSG00000175356
Variants:
dbSNP: 57758
ClinVar: 57758
TCGA: ENSG00000175356
COSMIC: SCUBE2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37142671 | 2023 | SCUBE2 mediates bone metastasis of luminal breast cancer by modulating immune-suppressive osteoblastic niches. | 11 |
| 37142671 | 2023 | SCUBE2 mediates bone metastasis of luminal breast cancer by modulating immune-suppressive osteoblastic niches. | 11 |
| 35904110 | 2022 | Knockdown of circ_0025908 inhibits proliferation, migration, invasion, and inflammation while stimulates apoptosis in fibroblast-like synoviocytes by regulating miR-650-dependent SCUBE2. | 2 |
| 35904110 | 2022 | Knockdown of circ_0025908 inhibits proliferation, migration, invasion, and inflammation while stimulates apoptosis in fibroblast-like synoviocytes by regulating miR-650-dependent SCUBE2. | 2 |
| 33878879 | 2021 | Expression of SCUBE2 and BCL2 Predicts Favorable Response in ERα Positive Breast Cancer. | 6 |
| 33878879 | 2021 | Expression of SCUBE2 and BCL2 Predicts Favorable Response in ERα Positive Breast Cancer. | 6 |
| 31991528 | 2020 | The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients. | 1 |
| 32293498 | 2020 | Knockdown of long non-coding RNA PVT1 induces apoptosis of fibroblast-like synoviocytes through modulating miR-543-dependent SCUBE2 in rheumatoid arthritis. | 16 |
| 31991528 | 2020 | The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients. | 1 |
| 32293498 | 2020 | Knockdown of long non-coding RNA PVT1 induces apoptosis of fibroblast-like synoviocytes through modulating miR-543-dependent SCUBE2 in rheumatoid arthritis. | 16 |
| 31404982 | 2019 | The Inhibitory Effect of (-)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing SCUBE2 Methylation and DNMT Activity. | 28 |
| 31425950 | 2019 | Upregulation of SCUBE2 expression in dyslipidemic type 2 diabetes mellitus is associated with endothelin-1. | 2 |
| 31404982 | 2019 | The Inhibitory Effect of (-)-Epigallocatechin-3-Gallate on Breast Cancer Progression via Reducing SCUBE2 Methylation and DNMT Activity. | 28 |
| 31425950 | 2019 | Upregulation of SCUBE2 expression in dyslipidemic type 2 diabetes mellitus is associated with endothelin-1. | 2 |
| 29883759 | 2018 | SCUBE2 inhibits the proliferation, migration and invasion of human non-small cell lung cancer cells through regulation of the sonic hedgehog signaling pathway. | 7 |
Citation
Dessen P
SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50982/scube2
