SEC14L2 (SEC14 like lipid binding 2)

2007-02-01  

Identity

HGNC
LOCATION
22q12.2
LOCUSID
ALIAS
C22orf6,SPF,TAP,TAP1
FUSION GENES

Other Information

Locus ID:

NCBI: 23541
MIM: 607558
HGNC: 10699
Ensembl: ENSG00000100003

Variants:

dbSNP: 23541
ClinVar: 23541
TCGA: ENSG00000100003
COSMIC: SEC14L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100003ENST00000402592O76054
ENSG00000100003ENST00000405717O76054
ENSG00000100003ENST00000415072C9JTM4
ENSG00000100003ENST00000428195C9JZI9
ENSG00000100003ENST00000429917C9JYY7
ENSG00000100003ENST00000437022F8WEE7
ENSG00000100003ENST00000452649F8WED8
ENSG00000100003ENST00000615189O76054
ENSG00000100003ENST00000615189A0A024R1I5
ENSG00000100003ENST00000617837B3KRD8

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
262669802015SEC14L2 enables pan-genotype HCV replication in cell culture.35
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
191903442009Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk.21
191903442009Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk.21
124290942002Crystal structure of the human supernatant protein factor.18
162670022005Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway.18
129722482003Supernatant protein factor in complex with RRR-alpha-tocopherylquinone: a link between oxidized Vitamin E and cholesterol biosynthesis.13
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.12
234016522013Effects of polymorphisms in vitamin E-, vitamin C-, and glutathione peroxidase-related genes on serum biomarkers and associations with glaucoma.10

Citation

Dessen P

SEC14L2 (SEC14 like lipid binding 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46542/sec14l2