SENP6 (SUMO specific peptidase 6)

2003-02-01  

Identity

HGNC
LOCATION
6q14.1
LOCUSID
ALIAS
SSP1,SUSP1
FUSION GENES

Other Information

Locus ID:

NCBI: 26054
MIM: 605003
HGNC: 20944
Ensembl: ENSG00000112701

Variants:

dbSNP: 26054
ClinVar: 26054
TCGA: ENSG00000112701
COSMIC: SENP6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112701ENST00000327284F8W6D9
ENSG00000112701ENST00000370010Q9GZR1
ENSG00000112701ENST00000424947H0Y4F4
ENSG00000112701ENST00000447266Q9GZR1
ENSG00000112701ENST00000483859D6RG09
ENSG00000112701ENST00000493959D6RJH1
ENSG00000112701ENST00000503501H0Y8Y8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380629722024[Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy].0
380629722024[Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy].0
367688782023SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis.1
367688782023SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis.1
350224082022Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.12
362926452022Single Cell RNA-Seq Identifies Immune-Related Prognostic Model and Key Signature-SPP1 in Pancreatic Ductal Adenocarcinoma.8
350224082022Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.12
362926452022Single Cell RNA-Seq Identifies Immune-Related Prognostic Model and Key Signature-SPP1 in Pancreatic Ductal Adenocarcinoma.8
319806332020Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin.17
319806332020Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin.17
306311522019SENP6-mediated M18BP1 deSUMOylation regulates CENP-A centromeric localization.16
307206882019Tolerance Biomarkers in Liver Transplantation: Independent External Validation of the Predictive Strength of SENP6 and FEM1C Gene Expression.9
314850032019The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation.31
315971052019The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics.27
306311522019SENP6-mediated M18BP1 deSUMOylation regulates CENP-A centromeric localization.16

Citation

Dessen P

SENP6 (SUMO specific peptidase 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42259/senp6