SENP7 (SUMO specific peptidase 7)

2013-01-01  

Identity

HGNC
LOCATION
3q12.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57337
MIM: 612846
HGNC: 30402
Ensembl: ENSG00000138468

Variants:

dbSNP: 57337
ClinVar: 57337
TCGA: ENSG00000138468
COSMIC: SENP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138468ENST00000314261Q9BQF6
ENSG00000138468ENST00000348610Q9BQF6
ENSG00000138468ENST00000366089H7C1X8
ENSG00000138468ENST00000394085Q9BQF6
ENSG00000138468ENST00000394091Q9BQF6
ENSG00000138468ENST00000394094J3QT09
ENSG00000138468ENST00000394095Q9BQF6

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351434212022SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells.23
351434212022SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells.23
318258332019DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells.14
318258332019DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells.14
297777122018Speckle-type POZ protein suppresses hepatocellular carcinoma cell migration and invasion via ubiquitin-dependent proteolysis of SUMO1/sentrin specific peptidase 7.15
297777122018Speckle-type POZ protein suppresses hepatocellular carcinoma cell migration and invasion via ubiquitin-dependent proteolysis of SUMO1/sentrin specific peptidase 7.15
284297432017Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation.9
284297432017Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation.9
258951362015c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4.51
258951362015c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4.51
240184222013The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair.50
240184222013The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair.50
230456452012Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition.43
230456452012Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition.43
218786242011Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7.17

Citation

Dessen P

SENP7 (SUMO specific peptidase 7)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53148/senp7