SERBP1 (SERPINE1 mRNA binding protein 1)

2007-02-01  

Identity

HGNC
SERBP1
LOCATION
1p31.3
LOCUSID
26135
ALIAS
CGI-55,CHD3IP,HABP4L,PAI-RBP1,PAIRBP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26135
MIM: 607378
HGNC: 17860
Ensembl: ENSG00000142864

Variants:

dbSNP: 26135
ClinVar: 26135
TCGA: ENSG00000142864
COSMIC: SERBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142864ENST00000361219Q8NC51
ENSG00000142864ENST00000370990Q8NC51
ENSG00000142864ENST00000370994Q8NC51
ENSG00000142864ENST00000370994Q5VU21
ENSG00000142864ENST00000370995Q8NC51

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
286571472018LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448.46
110019482001Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA.38
184401262008Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human.29
243749782014A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma.24
125051512003Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3.20
176981762007Expression analysis and RNA localization of PAI-RBP1 (SERBP1) in epithelial ovarian cancer: association with tumor progression.17
224420492012Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution.13
166795342006CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus.12
168796142006Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation.10
169632922006Relationship between polymorphisms in thrombophilic genes and preeclampsia in a Brazilian population.9

Citation

Dessen P

SERBP1 (SERPINE1 mRNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45522/serbp1