SERGEF (secretion regulating guanine nucleotide exchange factor)

2014-08-01  

Identity

HGNC
SERGEF
LOCATION
11p15.1
LOCUSID
26297
ALIAS
DELGEF,Gnefr
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26297
MIM: 606051
HGNC: 17499
Ensembl: ENSG00000129158

Variants:

dbSNP: 26297
ClinVar: 26297
TCGA: ENSG00000129158
COSMIC: SERGEF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129158ENST00000265965Q9UGK8
ENSG00000129158ENST00000524716E9PIU4
ENSG00000129158ENST00000525422G3V1B4
ENSG00000129158ENST00000525920H0YEV5
ENSG00000129158ENST00000527494E9PL52
ENSG00000129158ENST00000528200Q9UGK8
ENSG00000129158ENST00000529151H0YEL8
ENSG00000129158ENST00000529728E9PMV6
ENSG00000129158ENST00000530613E9PR50
ENSG00000129158ENST00000530925E9PIV0
ENSG00000129158ENST00000532265B4DFC0
ENSG00000129158ENST00000532389E9PS70
ENSG00000129158ENST00000532546H0YD20
ENSG00000129158ENST00000533241H0YE53
ENSG00000129158ENST00000533328H0YDC8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
124594922002DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.3

Citation

Dessen P

SERGEF (secretion regulating guanine nucleotide exchange factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54610/sergef