Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SERPINA10 (serpin family A member 10)

Identity

Alias_namesserine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
Alias_symbol (synonym)PZI
ZPI
Other alias
HGNC (Hugo) SERPINA10
LocusID (NCBI) 51156
Atlas_Id 52115
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 94283313 and ends at 94293024 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SERPINA10   15996
Cards
Entrez_Gene (NCBI)SERPINA10  51156  serpin family A member 10
AliasesPZI; ZPI
GeneCards (Weizmann)SERPINA10
Ensembl hg19 (Hinxton)ENSG00000140093 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140093 [Gene_View]  ENSG00000140093 [Sequence]  chr14:94283313-94293024 [Contig_View]  SERPINA10 [Vega]
ICGC DataPortalENSG00000140093
TCGA cBioPortalSERPINA10
AceView (NCBI)SERPINA10
Genatlas (Paris)SERPINA10
WikiGenes51156
SOURCE (Princeton)SERPINA10
Genetics Home Reference (NIH)SERPINA10
Genomic and cartography
GoldenPath hg38 (UCSC)SERPINA10  -     chr14:94283313-94293024 -  14q32.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SERPINA10  -     14q32.13   [Description]    (hg19-Feb_2009)
GoldenPathSERPINA10 - 14q32.13 [CytoView hg19]  SERPINA10 - 14q32.13 [CytoView hg38]
ImmunoBaseENSG00000140093
Mapping of homologs : NCBISERPINA10 [Mapview hg19]  SERPINA10 [Mapview hg38]
OMIM605271   
Gene and transcription
Genbank (Entrez)AF181467 AI174900 AK314877 AY358597 BC022261
RefSeq transcript (Entrez)NM_001100607 NM_016186
RefSeq genomic (Entrez)NC_000014 NG_021202 NT_187601
Consensus coding sequences : CCDS (NCBI)SERPINA10
Cluster EST : UnigeneHs.118620 [ NCBI ]
CGAP (NCI)Hs.118620
Alternative Splicing GalleryENSG00000140093
Gene ExpressionSERPINA10 [ NCBI-GEO ]   SERPINA10 [ EBI - ARRAY_EXPRESS ]   SERPINA10 [ SEEK ]   SERPINA10 [ MEM ]
Gene Expression Viewer (FireBrowse)SERPINA10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51156
GTEX Portal (Tissue expression)SERPINA10
Human Protein AtlasENSG00000140093-SERPINA10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UK55   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UK55  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UK55
Splice isoforms : SwissVarQ9UK55
PhosPhoSitePlusQ9UK55
Domains : Interpro (EBI)Serpin_dom    Serpin_fam    Serpin_sf    SERPINA10   
Domain families : Pfam (Sanger)Serpin (PF00079)   
Domain families : Pfam (NCBI)pfam00079   
Domain families : Smart (EMBL)SERPIN (SM00093)  
Conserved Domain (NCBI)SERPINA10
DMDM Disease mutations51156
Blocks (Seattle)SERPINA10
PDB (RSDB)3F1S    3H5C    4AFX    4AJU   
PDB Europe3F1S    3H5C    4AFX    4AJU   
PDB (PDBSum)3F1S    3H5C    4AFX    4AJU   
PDB (IMB)3F1S    3H5C    4AFX    4AJU   
Structural Biology KnowledgeBase3F1S    3H5C    4AFX    4AJU   
SCOP (Structural Classification of Proteins)3F1S    3H5C    4AFX    4AJU   
CATH (Classification of proteins structures)3F1S    3H5C    4AFX    4AJU   
SuperfamilyQ9UK55
Human Protein Atlas [tissue]ENSG00000140093-SERPINA10 [tissue]
Peptide AtlasQ9UK55
HPRD09245
IPIIPI00007199   IPI01026485   
Protein Interaction databases
DIP (DOE-UCLA)Q9UK55
IntAct (EBI)Q9UK55
FunCoupENSG00000140093
BioGRIDSERPINA10
STRING (EMBL)SERPINA10
ZODIACSERPINA10
Ontologies - Pathways
QuickGOQ9UK55
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular space  endoplasmic reticulum lumen  blood coagulation  heparin binding  negative regulation of endopeptidase activity  post-translational protein modification  cellular protein metabolic process  regulation of acrosome reaction  extracellular exosome  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular space  endoplasmic reticulum lumen  blood coagulation  heparin binding  negative regulation of endopeptidase activity  post-translational protein modification  cellular protein metabolic process  regulation of acrosome reaction  extracellular exosome  
NDEx NetworkSERPINA10
Atlas of Cancer Signalling NetworkSERPINA10
Wikipedia pathwaysSERPINA10
Orthology - Evolution
OrthoDB51156
GeneTree (enSembl)ENSG00000140093
Phylogenetic Trees/Animal Genes : TreeFamSERPINA10
HOGENOMQ9UK55
Homologs : HomoloGeneSERPINA10
Homology/Alignments : Family Browser (UCSC)SERPINA10
Gene fusions - Rearrangements
Fusion : QuiverSERPINA10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSERPINA10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SERPINA10
dbVarSERPINA10
ClinVarSERPINA10
1000_GenomesSERPINA10 
Exome Variant ServerSERPINA10
ExAC (Exome Aggregation Consortium)ENSG00000140093
GNOMAD BrowserENSG00000140093
Varsome BrowserSERPINA10
Genetic variants : HAPMAP51156
Genomic Variants (DGV)SERPINA10 [DGVbeta]
DECIPHERSERPINA10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSERPINA10 
Mutations
ICGC Data PortalSERPINA10 
TCGA Data PortalSERPINA10 
Broad Tumor PortalSERPINA10
OASIS PortalSERPINA10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSERPINA10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSERPINA10
Mutations and Diseases : HGMDSERPINA10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SERPINA10
DgiDB (Drug Gene Interaction Database)SERPINA10
DoCM (Curated mutations)SERPINA10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SERPINA10 (select a term)
intoGenSERPINA10
Cancer3DSERPINA10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605271   
Orphanet
DisGeNETSERPINA10
MedgenSERPINA10
Genetic Testing Registry SERPINA10
NextProtQ9UK55 [Medical]
TSGene51156
GENETestsSERPINA10
Target ValidationSERPINA10
Huge Navigator SERPINA10 [HugePedia]
snp3D : Map Gene to Disease51156
BioCentury BCIQSERPINA10
ClinGenSERPINA10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51156
Chemical/Pharm GKB GenePA38078
Clinical trialSERPINA10
Miscellaneous
canSAR (ICR)SERPINA10 (select the gene name)
DataMed IndexSERPINA10
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSERPINA10
EVEXSERPINA10
GoPubMedSERPINA10
iHOPSERPINA10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 18:06:51 CET 2019
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