Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5271
MIM: 601697
HGNC: 8952
Ensembl: ENSG00000166401
Variants:
dbSNP: 5271
ClinVar: 5271
TCGA: ENSG00000166401
COSMIC: SERPINB8
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Dissolution of Fibrin Clot | REACTOME | R-HSA-75205 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36134483 | 2023 | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | 1 |
| 37272794 | 2023 | Inhibition of Infectious HIV-1 Production by Rerouting the Cellular Furin Inhibitor Serpin B8. | 1 |
| 36134483 | 2023 | SERPINB8 and furin regulate ITGAX expression and affect the proliferation and invasion of melanoma cells. | 1 |
| 37272794 | 2023 | Inhibition of Infectious HIV-1 Production by Rerouting the Cellular Furin Inhibitor Serpin B8. | 1 |
| 27476651 | 2016 | Loss-of-Function Mutations in SERPINB8 Linked to Exfoliative Ichthyosis with Impaired Mechanical Stability of Intercellular Adhesions. | 12 |
| 27476651 | 2016 | Loss-of-Function Mutations in SERPINB8 Linked to Exfoliative Ichthyosis with Impaired Mechanical Stability of Intercellular Adhesions. | 12 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20953187 | 2010 | Association analyses identify six new psoriasis susceptibility loci in the Chinese population. | 118 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20953187 | 2010 | Association analyses identify six new psoriasis susceptibility loci in the Chinese population. | 118 |
| 19023099 | 2009 | Gene variants associated with ischemic stroke: the cardiovascular health study. | 20 |
| 19188865 | 2009 | Serine protease inhibitor 8 is a novel immunohistochemical marker for neuroendocrine tumors of the pancreas. | 1 |
| 19023099 | 2009 | Gene variants associated with ischemic stroke: the cardiovascular health study. | 20 |
| 19188865 | 2009 | Serine protease inhibitor 8 is a novel immunohistochemical marker for neuroendocrine tumors of the pancreas. | 1 |
| 17975119 | 2008 | Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. | 77 |
Citation
Dessen P
SERPINB8 (serpin family B member 8)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50950/serpinb8
