Identity
HGNC
LOCATION
2q36.1
LOCUSID
ALIAS
GDN,GDNPF,PI-7,PI7,PN-1,PN1,PNI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5270
MIM: 177010
HGNC: 8951
Ensembl: ENSG00000135919
Variants:
dbSNP: 5270
ClinVar: 5270
TCGA: ENSG00000135919
COSMIC: SERPINE2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38383657 | 2024 | Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers. | 0 |
| 38407942 | 2024 | SERPINE2 promotes liver cancer metastasis by inhibiting c-Cbl-mediated EGFR ubiquitination and degradation. | 3 |
| 38383657 | 2024 | Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B biomarkers. | 0 |
| 38407942 | 2024 | SERPINE2 promotes liver cancer metastasis by inhibiting c-Cbl-mediated EGFR ubiquitination and degradation. | 3 |
| 36797769 | 2023 | Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-????B-IL-6 axis of tumor-associated macrophages. | 14 |
| 37729702 | 2023 | Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profiling. | 1 |
| 36797769 | 2023 | Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-????B-IL-6 axis of tumor-associated macrophages. | 14 |
| 37729702 | 2023 | Microdissection of cancer-associated fibroblast infiltration subtypes unveils the secreted SERPINE2 contributing to immunosuppressive microenvironment and immuotherapeutic resistance in gastric cancer: A large-scale study integrating bulk and single-cell transcriptome profiling. | 1 |
| 34648881 | 2022 | SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer. | 25 |
| 35356880 | 2022 | [Bioinformatic analysis of immune correlation and prognostic value of SERPINs in glioma]. | 1 |
| 36505099 | 2022 | Upregulation of SERPINE2 Results in Poor Prognosis of Hepatoblastoma via Promoting Invasion Abilities. | 2 |
| 34648881 | 2022 | SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer. | 25 |
| 35356880 | 2022 | [Bioinformatic analysis of immune correlation and prognostic value of SERPINs in glioma]. | 1 |
| 36505099 | 2022 | Upregulation of SERPINE2 Results in Poor Prognosis of Hepatoblastoma via Promoting Invasion Abilities. | 2 |
| 33760135 | 2021 | SERPINE2 feedback regulates EGF/EGFR signaling in human papillary thyroid carcinoma cells. | 3 |
Citation
Dessen P
SERPINE2 (serpin family E member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49888/serpine2
