Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27244
MIM: 606103
HGNC: 21595
Ensembl: ENSG00000080546
Variants:
dbSNP: 27244
ClinVar: 27244
TCGA: ENSG00000080546
COSMIC: SESN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000080546 | ENST00000302071 | Q9Y6P5 |
| ENSG00000080546 | ENST00000356644 | Q9Y6P5 |
| ENSG00000080546 | ENST00000436639 | Q9Y6P5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38460759 | 2024 | IGF2BP3 stabilizes SESN1 mRNA to mitigate oxidized low-density lipoprotein-induced oxidative stress and endothelial dysfunction in human umbilical vein endothelial cells by activating Nrf2 signaling. | 0 |
| 38460759 | 2024 | IGF2BP3 stabilizes SESN1 mRNA to mitigate oxidized low-density lipoprotein-induced oxidative stress and endothelial dysfunction in human umbilical vein endothelial cells by activating Nrf2 signaling. | 0 |
| 37199024 | 2023 | SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing. | 5 |
| 38019229 | 2023 | Metformin Caused Radiosensitivity of Breast Cancer Cells through the Expression Modulation of miR-21-5p/SESN1axis. | 1 |
| 37199024 | 2023 | SESN1 is a FOXO3 effector that counteracts human skeletal muscle ageing. | 5 |
| 38019229 | 2023 | Metformin Caused Radiosensitivity of Breast Cancer Cells through the Expression Modulation of miR-21-5p/SESN1axis. | 1 |
| 34979914 | 2022 | The functions and roles of sestrins in regulating human diseases. | 23 |
| 35162104 | 2022 | Serum Sestrin-1 Concentration Is Higher in Frail than Non-Frail Older People Living in Nursing Homes. | 1 |
| 35293601 | 2022 | SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling. | 3 |
| 35622213 | 2022 | SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3. | 0 |
| 34979914 | 2022 | The functions and roles of sestrins in regulating human diseases. | 23 |
| 35162104 | 2022 | Serum Sestrin-1 Concentration Is Higher in Frail than Non-Frail Older People Living in Nursing Homes. | 1 |
| 35293601 | 2022 | SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling. | 3 |
| 35622213 | 2022 | SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3. | 0 |
| 33883304 | 2021 | Inhibition of sestrin 1 alleviates polycystic ovary syndrome by decreasing autophagy. | 3 |
Citation
Dessen P
SESN1 (sestrin 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42271/sesn1
