SF3A3 (splicing factor 3a subunit 3)

2014-08-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
PRP9,PRPF9,SAP61,SF3a60
FUSION GENES

Other Information

Locus ID:

NCBI: 10946
MIM: 605596
HGNC: 10767
Ensembl: ENSG00000183431

Variants:

dbSNP: 10946
ClinVar: 10946
TCGA: ENSG00000183431
COSMIC: SF3A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183431ENST00000373019Q12874

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, U2-snRNPKEGGhsa_M00352
Spliceosome, U2-snRNPKEGGM00352
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
156473712005Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.63
187130182008Specific inhibition of transcriptional activity of the constitutive androstane receptor (CAR) by the splicing factor SF3a3.1
271488592017Cellular stress response 1 down-regulates the expression of epidermal growth factor receptor and platelet-derived growth factor receptor through inactivation of splicing factor 3A3.0

Citation

Dessen P

SF3A3 (splicing factor 3a subunit 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54613/sf3a3