SFXN1 (sideroflexin 1)

2014-11-01  

Identity

HGNC
SFXN1
LOCATION
5q35.2
LOCUSID
94081
ALIAS
SLC56A1,TCC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 94081
MIM: 615569
HGNC: 16085
Ensembl: ENSG00000164466

Variants:

dbSNP: 94081
ClinVar: 94081
TCGA: ENSG00000164466
COSMIC: SFXN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164466ENST00000321442Q9H9B4
ENSG00000164466ENST00000502393S4R2X2
ENSG00000164466ENST00000502865H0Y9J5
ENSG00000164466ENST00000506963D6RFI0
ENSG00000164466ENST00000507017D6RDG7
ENSG00000164466ENST00000507823D6RAE9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
304427782018SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.17

Citation

Dessen P

SFXN1 (sideroflexin 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73173/sfxn1