SGSM3 (small G protein signaling modulator 3)

2014-04-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
CIP85,MAP,RABGAP5,RUSC3,RUTBC3,RabGAP-5,rabGAPLP
FUSION GENES

Other Information

Locus ID:

NCBI: 27352
MIM: 610440
HGNC: 25228
Ensembl: ENSG00000100359

Variants:

dbSNP: 27352
ClinVar: 27352
TCGA: ENSG00000100359
COSMIC: SGSM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100359ENST00000248929Q96HU1
ENSG00000100359ENST00000248929B9A6J5
ENSG00000100359ENST00000417424H0Y7V2
ENSG00000100359ENST00000427834B0QY81
ENSG00000100359ENST00000457767B0QY80

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
175098192007Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.22
239183012014Association between an insertion/deletion polymorphism within 3'UTR of SGSM3 and risk of hepatocellular carcinoma.10
235867102013The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane.9
296937422018Evaluation of 4-bp insertion/deletion polymorphism within the 3'UTR of SGSM3 in bladder cancer using mismatch PCR-RFLP method: A preliminary report.4
155413572004MAP, a protein interacting with a tumor suppressor, merlin, through the run domain.1
274322652017Genetic variants of ESR1 and SGSM3 are associated with the susceptibility of breast cancer in the Chinese population.1

Citation

Dessen P

SGSM3 (small G protein signaling modulator 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-04-01

Online version: http://atlasgeneticsoncology.org/gene/53858/sgsm3