SH3YL1 (SH3 and SYLF domain containing 1)

2014-08-01  

Identity

HGNC
SH3YL1
LOCATION
2p25.3
LOCUSID
26751
ALIAS
RAY
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26751
MIM: 617314
HGNC: 29546
Ensembl: ENSG00000035115

Variants:

dbSNP: 26751
ClinVar: 26751
TCGA: ENSG00000035115
COSMIC: SH3YL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000035115ENST00000356150Q96HL8
ENSG00000035115ENST00000402632Q96HL8
ENSG00000035115ENST00000403657Q96HL8
ENSG00000035115ENST00000403658Q96HL8
ENSG00000035115ENST00000403712Q96HL8
ENSG00000035115ENST00000405430Q96HL8
ENSG00000035115ENST00000415368C9J4Z8
ENSG00000035115ENST00000431160H7C1B8
ENSG00000035115ENST00000451005H7C499
ENSG00000035115ENST00000454318C9JJI3
ENSG00000035115ENST00000479739F5GYQ6
ENSG00000035115ENST00000481932S4R3I7
ENSG00000035115ENST00000626873Q96HL8

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
216249562011SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain.30
245084792014Dock4 forms a complex with SH3YL1 and regulates cancer cell migration.9
263056792015Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.5

Citation

Dessen P

SH3YL1 (SH3 and SYLF domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54618/sh3yl1