SHROOM2 (shroom family member 2)

2014-11-01  

Identity

HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
APXL,HSAPXL
FUSION GENES

Other Information

Locus ID:

NCBI: 357
MIM: 300103
HGNC: 630
Ensembl: ENSG00000146950

Variants:

dbSNP: 357
ClinVar: 357
TCGA: ENSG00000146950
COSMIC: SHROOM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146950ENST00000380913Q13796
ENSG00000146950ENST00000418909F5H3B6
ENSG00000146950ENST00000452575C9IZC6

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
226347552012Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.119
212482032011Shroom2 regulates contractility to control endothelial morphogenesis.23
306838442019SHROOM2 inhibits tumor metastasis through RhoA-ROCK pathway-dependent and -independent mechanisms in nasopharyngeal carcinoma.4
294236512018Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort.2
301608332018Ocular albinism with infertility and late-onset sensorineural hearing loss.1

Citation

Dessen P

SHROOM2 (shroom family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73235/shroom2