SINHCAF (SIN3-HDAC complex associated factor)

2017-10-01  

Identity

HGNC
SINHCAF
LOCATION
12p11.21
LOCUSID
58516
ALIAS
C12orf14,FAM60A,L4,TERA

Other Information

Locus ID:

NCBI: 58516
MIM: 615027
HGNC: 30702
Ensembl: ENSG00000139146

Variants:

dbSNP: 58516
ClinVar: 58516
TCGA: ENSG00000139146
COSMIC: SINHCAF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139146ENST00000337682Q9NP50
ENSG00000139146ENST00000454658Q9NP50
ENSG00000139146ENST00000539004F5GZ82
ENSG00000139146ENST00000539409Q9NP50
ENSG00000139146ENST00000542983Q9NP50
ENSG00000139146ENST00000543615F5H6U2
ENSG00000139146ENST00000544921H0YGG0

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
229842882012Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.18
228658852012Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.15
281693572017Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy.7
297848892018SINHCAF/FAM60A and SIN3A specifically repress HIF-2α expression.3

Citation

Dessen P

SINHCAF (SIN3-HDAC complex associated factor)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57061/sinhcaf