SLAMF1 (signaling lymphocytic activation molecule family member 1)

2003-11-01  

Identity

HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
CD150,CDw150,SLAM
FUSION GENES

Other Information

Locus ID:

NCBI: 6504
MIM: 603492
HGNC: 10903
Ensembl: ENSG00000117090

Variants:

dbSNP: 6504
ClinVar: 6504
TCGA: ENSG00000117090
COSMIC: SLAMF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117090ENST00000235739Q96QJ2
ENSG00000117090ENST00000302035Q13291
ENSG00000117090ENST00000538290Q13291

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
MeaslesKEGGko05162
MeaslesKEGGhsa05162

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200425012010Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150).47
182872342008Measles virus infects both polarized epithelial and immune cells by using distinctive receptor-binding sites on its hemagglutinin.45
177152172007A human lung carcinoma cell line supports efficient measles virus growth and syncytium formation via a SLAM- and CD46-independent mechanism.37
220863892011The association of CD46, SLAM and CD209 cellular receptor gene SNPs with variations in measles vaccine-induced immune responses: a replication study and examination of novel polymorphisms.37
153087012004Measles virus (MV) hemagglutinin: evidence that attachment sites for MV receptors SLAM and CD46 overlap on the globular head.33
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
175606392007Variations in measles vaccine-specific humoral immunity by polymorphisms in SLAM and CD46 measles virus receptors.28
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
214508132011Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.27

Citation

Dessen P

SLAMF1 (signaling lymphocytic activation molecule family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/42309/slamf1