Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
CTC-479C5.17,KCC1,hKCC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6560
MIM: 604119
HGNC: 10913
Ensembl: ENSG00000124067
Variants:
dbSNP: 6560
ClinVar: 6560
TCGA: ENSG00000124067
COSMIC: SLC12A4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35759661 | 2022 | Structure of the human cation-chloride cotransport KCC1 in an outward-open state. | 9 |
| 35759661 | 2022 | Structure of the human cation-chloride cotransport KCC1 in an outward-open state. | 9 |
| 31296230 | 2019 | K(+)-Cl(-) cotransporter 1 (KCC1): a housekeeping membrane protein that plays key supplemental roles in hematopoietic and cancer cells. | 10 |
| 31296230 | 2019 | K(+)-Cl(-) cotransporter 1 (KCC1): a housekeeping membrane protein that plays key supplemental roles in hematopoietic and cancer cells. | 10 |
| 28093242 | 2017 | The Zn(2+)-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl(-) absorption, via basolateral KCC1, and reduces fluid loss. | 15 |
| 28093242 | 2017 | The Zn(2+)-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl(-) absorption, via basolateral KCC1, and reduces fluid loss. | 15 |
| 21613606 | 2011 | Similar effects of all WNK3 variants on SLC12 cotransporters. | 14 |
| 21666489 | 2011 | KCC1 gene advances cell invasion ability by regulating ERK signaling pathway in endometrial cancer HEC-1B cell line. | 1 |
| 21733850 | 2011 | K-Cl cotransporter gene expression during human and murine erythroid differentiation. | 15 |
| 21613606 | 2011 | Similar effects of all WNK3 variants on SLC12 cotransporters. | 14 |
| 21666489 | 2011 | KCC1 gene advances cell invasion ability by regulating ERK signaling pathway in endometrial cancer HEC-1B cell line. | 1 |
| 21733850 | 2011 | K-Cl cotransporter gene expression during human and murine erythroid differentiation. | 15 |
| 20602615 | 2010 | Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? | 3 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20602615 | 2010 | Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? | 3 |
Citation
Dessen P
SLC12A4 (solute carrier family 12 member 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45800/slc12a4
