SLC22A9 (solute carrier family 22 member 9)

2014-11-01  

Identity

HGNC
LOCATION
11q12.3
LOCUSID
ALIAS
HOAT4,OAT4,OAT7,UST3H,ust3

Other Information

Locus ID:

NCBI: 114571
MIM: 607579
HGNC: 16261
Ensembl: ENSG00000149742

Variants:

dbSNP: 114571
ClinVar: 114571
TCGA: ENSG00000149742
COSMIC: SLC22A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149742ENST00000279178Q8IVM8
ENSG00000149742ENST00000536333Q8IVM8

Expression (GTEx)

0
5
10
15

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA450428methotrexateChemicalPathwayassociated25502615

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
124092832003Characterization and identification of steroid sulfate transporters of human placenta.34
173935042007Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.32
184661052008Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.23
173415442007Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells.21
185015902008Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta.12
184147812008Analysis of regulatory polymorphisms in organic ion transporter genes (SLC22A) in the kidney.10
183652452008Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias.7
193712582009Human organic anion transporter hOAT4 is a transporter of perfluorooctanoic acid.7
262390792016Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors.7

Citation

Dessen P

SLC22A9 (solute carrier family 22 member 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73326/slc22a9