SLC25A21 (solute carrier family 25 member 21)

2014-11-01  

Identity

HGNC
LOCATION
14q13.3
LOCUSID
ALIAS
MTDPS18,ODC,ODC1
FUSION GENES

Other Information

Locus ID:

NCBI: 89874
MIM: 607571
HGNC: 14411
Ensembl: ENSG00000183032

Variants:

dbSNP: 89874
ClinVar: 89874
TCGA: ENSG00000183032
COSMIC: SLC25A21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183032ENST00000331299Q9BQT8
ENSG00000183032ENST00000555449Q9BQT8

Expression (GTEx)

0
1
2
3
4
5

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Lysine catabolismREACTOMER-HSA-71064
Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolismREACTOMER-HSA-6788656

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232661872013The mitochondrial transporter family SLC25: identification, properties and physiopathology.159
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
295177682018Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy-like disease.6

Citation

Dessen P

SLC25A21 (solute carrier family 25 member 21)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73344/slc25a21