SLC25A37 (solute carrier family 25 member 37)

2014-11-01  

Identity

HGNC
LOCATION
8p21.2
LOCUSID
ALIAS
HT015,MFRN,MFRN1,MSC,MSCP,PRO1278,PRO1584,PRO2217
FUSION GENES

Other Information

Locus ID:

NCBI: 51312
MIM: 610387
HGNC: 29786
Ensembl: ENSG00000147454

Variants:

dbSNP: 51312
ClinVar: 51312
TCGA: ENSG00000147454
COSMIC: SLC25A37

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147454ENST00000290075Q9NYZ2
ENSG00000147454ENST00000417331F8W9Q7
ENSG00000147454ENST00000519973Q9NYZ2
ENSG00000147454ENST00000523930H0YAT5

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Mitochondrial iron-sulfur cluster biogenesisREACTOMER-HSA-1362409

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232661872013The mitochondrial transporter family SLC25: identification, properties and physiopathology.159
216279782011Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
248549902015Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron.17
191872262009Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling.4
276434752016Identification of SLC25A37 as a major depressive disorder risk gene.3
303911632019Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria.0
307618712019The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients0

Citation

Dessen P

SLC25A37 (solute carrier family 25 member 37)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73357/slc25a37