SLC26A7 (solute carrier family 26 member 7)

2014-11-01 Affiliation

Identity

HGNC

SLC26A7

LOCATION

8q21.3

LOCUSID

115111

ALIAS

SUT2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 115111
MIM: 608479
HGNC: 14467
Ensembl: ENSG00000147606

Variants:

dbSNP: 115111
ClinVar: 115111
TCGA: ENSG00000147606
COSMIC: SLC26A7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000147606	ENST00000276609	Q8TE54
ENSG00000147606	ENST00000309536	Q8TE54
ENSG00000147606	ENST00000520818	H0YB61
ENSG00000147606	ENST00000522181	E5RGL8
ENSG00000147606	ENST00000522862	E5RFH2
ENSG00000147606	ENST00000523719	Q8TE54
ENSG00000147606	ENST00000617078	A0A087WZI7
ENSG00000147606	ENST00000617233	Q8TE54

Expression (GTEx)

100

150

200

250

300

350

400

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Gastric acid secretion	KEGG	ko04971
Gastric acid secretion	KEGG	hsa04971
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME	R-HSA-425393
Multifunctional anion exchangers	REACTOME	R-HSA-427601

References

Pubmed ID	Year	Title	Citations
16524946	2006	Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion.	9
11829495	2002	Molecular cloning of SLC26A7, a novel member of the SLC26 sulfate/anion transporter family, from high endothelial venules and kidney.	6
29546359	2018	Molecular Analysis of Congenital Hypothyroidism in Saudi Arabia: SLC26A7 Mutation Is a Novel Defect in Thyroid Dyshormonogenesis.	6
30333321	2018	Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism.	6
15956810	2005	SLC26A6 and SLC26A7 anion exchangers have a distinct distribution in human kidney.	4

Citation

Dessen P

SLC26A7 (solute carrier family 26 member 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73375/slc26a7