SLC30A7 (solute carrier family 30 member 7)

2014-08-01  

Identity

HGNC
LOCATION
1p21.2
LOCUSID
ALIAS
ZNT7,ZnT-7,ZnTL2
FUSION GENES

Other Information

Locus ID:

NCBI: 148867
MIM: 611149
HGNC: 19306
Ensembl: ENSG00000162695

Variants:

dbSNP: 148867
ClinVar: 148867
TCGA: ENSG00000162695
COSMIC: SLC30A7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162695ENST00000357650Q8NEW0
ENSG00000162695ENST00000370111H0Y362
ENSG00000162695ENST00000370112Q8NEW0

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Insulin processingREACTOMER-HSA-264876
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Metal ion SLC transportersREACTOMER-HSA-425410
Zinc transportersREACTOMER-HSA-435354
Zinc efflux and compartmentalization by the SLC30 familyREACTOMER-HSA-435368

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
214621062010Gastrointestinal factors influencing zinc absorption and homeostasis.24
179715002008Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9.22
186397462008Abundant expression of zinc transporters in the amyloid plaques of Alzheimer's disease brain.22
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.20
232750322013Zinc transporter 5 and zinc transporter 7 induced by high glucose protects peritoneal mesothelial cells from undergoing apoptosis.6
285583002017Urine cadmium levels and albuminuria in a general population from Spain: A gene-environment interaction analysis.5

Citation

Dessen P

SLC30A7 (solute carrier family 30 member 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54636/slc30a7