SLC35B2 (solute carrier family 35 member B2)

2011-06-01  

Identity

HGNC
SLC35B2
LOCATION
6p21.1
LOCUSID
347734
ALIAS
PAPST1,SLL,UGTrel4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 347734
MIM: 610788
HGNC: 16872
Ensembl: ENSG00000157593

Variants:

dbSNP: 347734
ClinVar: 347734
TCGA: ENSG00000157593
COSMIC: SLC35B2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000157593ENST00000393810A0A0A0MS46
ENSG00000157593ENST00000393812Q8TB61
ENSG00000157593ENST00000537814Q8TB61
ENSG00000157593ENST00000538577Q8TB61
ENSG00000157593ENST00000615337Q8TB61
ENSG00000157593ENST00000619636Q8TB61

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of nucleotide sugarsREACTOMER-HSA-727802
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Transport and synthesis of PAPSREACTOMER-HSA-174362
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
209780092011Expression and the role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma.7
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.6
127168892003Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter.0
245761812014MiR-22 is frequently downregulated in medulloblastomas and inhibits cell proliferation via the novel target PAPST1.0
251245742014SLC35B2 expression is associated with a poor prognosis of invasive ductal breast carcinoma.0

Citation

Dessen P

SLC35B2 (solute carrier family 35 member B2)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52238/slc35b2