Identity
HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
HCIN,HMNDYT2,LZT-Hs4,NET34,ZIP14,cig19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23516
MIM: 608736
HGNC: 20858
Ensembl: ENSG00000104635
Variants:
dbSNP: 23516
ClinVar: 23516
TCGA: ENSG00000104635
COSMIC: SLC39A14
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447278 | Depression | Disease | ClinicalAnnotation | associated | PD | 20970119 | |
| PA450657 | nortriptyline | Chemical | ClinicalAnnotation | associated | PD | 20970119 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34924116 | 2022 | Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP. | 13 |
| 35787370 | 2022 | Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells. | 6 |
| 36062189 | 2022 | Circ_000829 Plays an Anticancer Role in Renal Cell Carcinoma by Suppressing SRSF1-Mediated Alternative Splicing of SLC39A14. | 2 |
| 36361624 | 2022 | Hereditary Disorders of Manganese Metabolism: Pathophysiology of Childhood-Onset Dystonia-Parkinsonism in SLC39A14 Mutation Carriers and Genetic Animal Models. | 3 |
| 34924116 | 2022 | Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP. | 13 |
| 35787370 | 2022 | Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells. | 6 |
| 36062189 | 2022 | Circ_000829 Plays an Anticancer Role in Renal Cell Carcinoma by Suppressing SRSF1-Mediated Alternative Splicing of SLC39A14. | 2 |
| 36361624 | 2022 | Hereditary Disorders of Manganese Metabolism: Pathophysiology of Childhood-Onset Dystonia-Parkinsonism in SLC39A14 Mutation Carriers and Genetic Animal Models. | 3 |
| 33658057 | 2021 | Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis. | 4 |
| 34198528 | 2021 | HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn(2+) Accumulation in Inflammatory Synoviocytes. | 8 |
| 33658057 | 2021 | Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis. | 4 |
| 34198528 | 2021 | HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn(2+) Accumulation in Inflammatory Synoviocytes. | 8 |
| 32392784 | 2020 | The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis. | 25 |
| 32729666 | 2020 | Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA-502-5p-mediated inhibition of SLC39A14. | 17 |
| 33146651 | 2020 | Human placental cell line HTR-8/SVneo accumulates cadmium by divalent metal transporters DMT1 and ZIP14. | 9 |
Citation
Dessen P
SLC39A14 (solute carrier family 39 member 14)
Atlas Genet Cytogenet Oncol Haematol. 2011-04-01
Online version: http://atlasgeneticsoncology.org/gene/43062/slc39a14
