SLC7A10 (solute carrier family 7 member 10)

2014-11-01  

Identity

HGNC
LOCATION
19q13.11
LOCUSID
ALIAS
ASC1,HASC-1,asc-1

Other Information

Locus ID:

NCBI: 56301
MIM: 607959
HGNC: 11058
Ensembl: ENSG00000130876

Variants:

dbSNP: 56301
ClinVar: 56301
TCGA: ENSG00000130876
COSMIC: SLC7A10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130876ENST00000253188Q9NS82
ENSG00000130876ENST00000587064K7ENB6
ENSG00000130876ENST00000590036K7EK24
ENSG00000130876ENST00000592596K7ENB6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Amino acid transport across the plasma membraneREACTOMER-HSA-352230

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
250804782014ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.54
252194982014Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development.43
154584382004The amino acid transporter asc-1 is not involved in cystinuria.5
218889422011No genetic association between SLC7A10 and Japanese patients with schizophrenia.0
317940732020ASC-1 Is a Cell Cycle Regulator Associated with Severe and Mild Forms of Myopathy.0

Citation

Dessen P

SLC7A10 (solute carrier family 7 member 10)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73481/slc7a10