Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
E3KARP,NHE3RF2,NHERF-2,NHERF2,OCTS2,SIP-1,SIP1,TKA-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9351
MIM: 606553
HGNC: 11076
Ensembl: ENSG00000065054
Variants:
dbSNP: 9351
ClinVar: 9351
TCGA: ENSG00000065054
COSMIC: SLC9A3R2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Aldosterone-regulated sodium reabsorption | KEGG | ko04960 |
| Aldosterone-regulated sodium reabsorption | KEGG | hsa04960 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA27745 | ELF2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31597772 | 2019 | PDZ Domain-Containing Protein NHERF-2 Is a Novel Target of Human Papillomavirus 16 (HPV-16) and HPV-18. | 11 |
| 31597772 | 2019 | PDZ Domain-Containing Protein NHERF-2 Is a Novel Target of Human Papillomavirus 16 (HPV-16) and HPV-18. | 11 |
| 28392297 | 2017 | Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. | 6 |
| 28392297 | 2017 | Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. | 6 |
| 26310448 | 2015 | The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation. | 3 |
| 26310448 | 2015 | The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation. | 3 |
| 24613836 | 2014 | Structural insights into PDZ-mediated interaction of NHERF2 and LPA(2), a cellular event implicated in CFTR channel regulation. | 6 |
| 24760985 | 2014 | Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling. | 11 |
| 24613836 | 2014 | Structural insights into PDZ-mediated interaction of NHERF2 and LPA(2), a cellular event implicated in CFTR channel regulation. | 6 |
| 24760985 | 2014 | Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling. | 11 |
| 23612977 | 2013 | NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. | 13 |
| 23985317 | 2013 | The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics. | 14 |
| 23612977 | 2013 | NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. | 13 |
| 23985317 | 2013 | The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics. | 14 |
| 22343917 | 2012 | NHERF-2 maintains endothelial homeostasis. | 15 |
Citation
Dessen P
SLC9A3R2 (SLC9A3 regulator 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43686/slc9a3r2
