SLFN12 (schlafen family member 12)

2003-05-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
SLFN3

Other Information

Locus ID:

NCBI: 55106
MIM: 614955
HGNC: 25500
Ensembl: ENSG00000172123

Variants:

dbSNP: 55106
ClinVar: 55106
TCGA: ENSG00000172123
COSMIC: SLFN12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172123ENST00000304905Q8IYM2
ENSG00000172123ENST00000394562Q8IYM2
ENSG00000172123ENST00000445092C9JIA1
ENSG00000172123ENST00000447040C9J4K7
ENSG00000172123ENST00000452764Q8IYM2

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
247681412014Schlafen 12 expression modulates prostate cancer cell differentiation.9
291070682017Targeting tumor cells based on Phosphodiesterase 3A expression.9
300450192018Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation.8
314202162019Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.7
308750772019Schlafen 12 mediates the effects of butyrate and repetitive mechanical deformation on intestinal epithelial differentiation in human Caco-2 intestinal epithelial cells.2
310267792019Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation.0
318387902019Schlafen12 Reduces the Aggressiveness of Triple Negative Breast Cancer through Post-Transcriptional Regulation of ZEB1 That Drives Stem Cell Differentiation.0

Citation

Dessen P

SLFN12 (schlafen family member 12)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40581/slfn12