SLFN13 (schlafen family member 13)

2014-11-01  

Identity

HGNC
SLFN13
LOCATION
17q12
LOCUSID
146857
ALIAS
SLFN10,hSLFN13

Other Information

Locus ID:

NCBI: 146857
MIM: 614957
HGNC: 26481
Ensembl: ENSG00000154760

Variants:

dbSNP: 146857
ClinVar: 146857
TCGA: ENSG00000154760
COSMIC: SLFN13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154760ENST00000285013Q68D06
ENSG00000154760ENST00000524511E9PM29
ENSG00000154760ENST00000526861Q68D06
ENSG00000154760ENST00000530782E9PMV5
ENSG00000154760ENST00000531588K7EPV8
ENSG00000154760ENST00000532210E9PKT7
ENSG00000154760ENST00000533791Q68D06
ENSG00000154760ENST00000534689Q68D06
ENSG00000154760ENST00000542635Q68D06

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
295635502018Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.14

Citation

Dessen P

SLFN13 (schlafen family member 13)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73512/slfn13