Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23137
MIM: 609386
HGNC: 20465
Ensembl: ENSG00000198887
Variants:
dbSNP: 23137
ClinVar: 23137
TCGA: ENSG00000198887
COSMIC: SMC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198887 | ENST00000361138 | Q8IY18 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38375830 | 2024 | The SMC5/6 complex: folding chromosomes back into shape when genomes take a break. | 1 |
| 38375830 | 2024 | The SMC5/6 complex: folding chromosomes back into shape when genomes take a break. | 1 |
| 35894836 | 2023 | The structural maintenance of chromosomes 5 is a possible biomarker for individualized treatment of colorectal cancer. | 1 |
| 36627765 | 2023 | In-frame deletion of SMC5 related with the phenotype of primordial dwarfism, chromosomal instability and insulin resistance. | 5 |
| 35894836 | 2023 | The structural maintenance of chromosomes 5 is a possible biomarker for individualized treatment of colorectal cancer. | 1 |
| 36627765 | 2023 | In-frame deletion of SMC5 related with the phenotype of primordial dwarfism, chromosomal instability and insulin resistance. | 5 |
| 36333305 | 2022 | Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy. | 11 |
| 36376394 | 2022 | Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency. | 10 |
| 36333305 | 2022 | Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy. | 11 |
| 36376394 | 2022 | Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency. | 10 |
| 33811831 | 2021 | The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr. | 39 |
| 33811831 | 2021 | The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr. | 39 |
| 31867888 | 2020 | SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability. | 15 |
| 32320646 | 2020 | Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase. | 23 |
| 32389690 | 2020 | Molecular Insights into the Architecture of the Human SMC5/6 Complex. | 16 |
Citation
Dessen P
SMC5 (structural maintenance of chromosomes 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45967/smc5
