SNAPC4 (small nuclear RNA activating complex polypeptide 4)

2014-11-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
PTFalpha,SNAP190
FUSION GENES

Other Information

Locus ID:

NCBI: 6621
MIM: 602777
HGNC: 11137
Ensembl: ENSG00000165684

Variants:

dbSNP: 6621
ClinVar: 6621
TCGA: ENSG00000165684
COSMIC: SNAPC4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165684ENST00000298532Q5SXM2
ENSG00000165684ENST00000298532A0A024R8F4
ENSG00000165684ENST00000637388A0A1B0GUB4

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase III TranscriptionREACTOMER-HSA-74158
RNA Polymerase III Abortive And Retractive InitiationREACTOMER-HSA-749476
RNA Polymerase III Transcription InitiationREACTOMER-HSA-76046
RNA Polymerase III Transcription Initiation From Type 3 PromoterREACTOMER-HSA-76071
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
204637472010Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene.18
176707472007The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III.8
265908212016Determination of IL1 R2, ANTXR2, CARD9, and SNAPC4 single nucleotide polymorphisms in Iranian patients with ankylosing spondylitis.5
243346452014Evidence for genetic association of CARD9 and SNAPC4 with ankylosing spondylitis in a Chinese Han population.4
159558162005Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC.3

Citation

Dessen P

SNAPC4 (small nuclear RNA activating complex polypeptide 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73604/snapc4